oleanolicacid相关论文
Proliferation-Inhibiting and Apoptosis-Inducing Effects of Ursolic Acid and Oleanolic Acid on Multi-
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Synthesis and anti-hepatocellular carcinoma activity of novel O2-vinyl diazeniumdiolate-based nitric
Considering that high levels of nitric oxide (NO) exert anti-cancer effect and the derivatives of oleanolic acid (OA) ha......
Oleanolic acid (OA) is a pentacyclic triterpenoid compound extracted from olea europaeal, a traditional Chinese medicine......
The present study was designed to synthesize 2-Cyano-3,12-dioxooleana-1,9(11)-en-28-oate-13β,28-olide (1),a lactone der......
Glucosamine-6 phosphate synthase(GlmS)is the first enzyme of the hexosamine biosynthetic pathway.This enzyme catalyzes t......
Inhibition of mTOR signaling by oleanolic acid contribute to its anti-tumor activity in osteosarcoma
Oleanolic acid (OA), a pentacyclic triterpenoid exhibits potent anti-tumor activity against diverse types of tumor cell ......
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A novel screening model for the molecular drug for diabetess and obesity based on tyrosine phosphata
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Identification of Nitric Oxide-Releasing Derivatives of Oleanolic Acid as Potential Anti-Colon Cance
The overexpressed GSTπ isozyme in tumor cells was regarded as targets for the design of anti-cancer agents.Herein,a gro......
Aim: Ursolic acid (UA) and oleanolic acid (OA) are steroisomers.Both are bioactive pentacyclic triterpenoids present in ......
Oleanolic acid (OA) exerts an osteoprotective effect in ovariectomy-induced osteoporotic mice and in
Osteoclast-induced bone disordering diseases, such as osteoporosis, are quite prevalent in modem society.However, the cu......
Objective: Oleanolic acid (OA) may have important activity relevant to health and disease prevention.Here we aimed to st......
Inhibition of mTOR Signaling by Oleanolic Acid Contributes to Its Anti-Tumor Activity in Osteosarcom
Oleanolic acid (OA), a pentacyclic triterpenoid exhibits potent anti-tumor activity against many tumor cell lines.But th......
Aim: To investigate the effect and possible mechanisms of oleanolic acid (OA) in preventing endothelial cell oxidative i......
Oleanolic acid attenuates insulin resistance via NF-kappaB to regulate IRS1-GLUT4 pathway in HepG2 c
Background:Insulin resistance (IR) is a risk factor for many clinical diseases,including type Ⅱ diabetes,hypertension,a......
NG, a novel PABA/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS
NG,a novel PABA/NO-based derivative of oleanolic acid (OA),has been found to show potent antitumor activity both in vivo......
Oleanolic Acid Suppresses Migration and Invasion of Malignant Glioma through Deactivating MAPK/ERK S
Mitogen-activated protein kinases/Extracellular signal-regulated kinase (MAPK/ERK) pathway is essential for migratory an......
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Distribution and Expression Characteristics of Triterpenoids and OSC genes in White Birch (Betula pl
Betulin and oleanolic acids (pentacyclic triterpenoid secondary metabolites) have broad pharmacological activities a......
A novel gem-difluoromethylenated oleanolic acid was synthesized and its anti-hepatocellular carcinoma activity in vi......
目的 研究齐墩果酸抗菌香皂体外抑菌活性和生物安全性.方法 采用琼脂扩散法和动物实验法,对该抗菌香皂体外抑菌效果和毒性进行了实......
恶性肿瘤已经成为严重威胁人类生命与健康的疾病之一,随着对恶性肿瘤治疗方面研究的不断进展,越来越多的抑制肿瘤的有效物质被发现。......
目的:建立蒙药材大托叶云实的质量标准,为控制和评价该药材质量提供有效的实验依据.方法:采用显微鉴别法对大托叶云实的显微特征进......
目的构建胆道结扎的胆汁淤积大鼠模型,研究齐墩果酸对急性胆汁淤积时胆酸排泌泵和核受体的影响。方法30只大鼠利用随机数字表法分为......
目的:安息香中分离提纯的齐墩果酸(Oleanolic acid)化合物体内外抗HSV-1活性,以及抗病毒机制的探究,为开发新型抗HSV-1药物奠定理......
Objective: To establish reliable methods for evaluating the quality of Chinese herb fructus chaenomelis. Methods: Qualit......
目的:对女贞子中主要药用成分进行定性分析,用电喷雾质谱法探究人血清白蛋白与齐墩果酸相互作用。方法:定性分析采用高效液相色谱......
本文综述了木瓜的生理活性物质-齐墩果酸的药用价值和作用机理以及木瓜药品保健品的研究动态和展望。......